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  5. CVE-2025-68463

CVE-2025-68463: Biopython is vulnerable to doctype XML external entity (XXE) injection through Bio.Entrez

December 18, 2025

Bio.Entrez in Biopython through 1.86 allows doctype XXE.

References

  • github.com/advisories/GHSA-x3vf-39hj-gxr4
  • github.com/biopython/biopython
  • github.com/biopython/biopython/issues/5109
  • nvd.nist.gov/vuln/detail/CVE-2025-68463

Code Behaviors & Features

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Affected versions

All versions up to 1.86

Solution

Unfortunately, there is no solution available yet.

Impact 4.9 MEDIUM

CVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:C/C:L/I:N/A:L

Learn more about CVSS

Weakness

  • CWE-611: Improper Restriction of XML External Entity Reference

Source file

pypi/biopython/CVE-2025-68463.yml

Spotted a mistake? Edit the file on GitLab.

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